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A human monoclonal antibody combination rescues nonhuman primates from advanced disease caused by the major lineages of Lassa virus
There are no approved treatments for Lassa fever (LF), which is responsible for thousands of deaths each year in West Africa. A major challenge in developing effective medical countermeasures against LF is the high diversity of circulating Lassa virus (LASV) strains with four recognized lineages and...
Autores principales: | Cross, Robert W., Heinrich, Megan L., Fenton, Karla A., Borisevich, Viktoriya, Agans, Krystle N., Prasad, Abhishek N., Woolsey, Courtney, Deer, Daniel J., Dobias, Natalie S., Rowland, Megan M., Lathigra, Raju, Borrega, Rodrigo, Geisbert, Joan B., Garry, Robert F., Branco, Luis M., Geisbert, Thomas W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450431/ https://www.ncbi.nlm.nih.gov/pubmed/37590417 http://dx.doi.org/10.1073/pnas.2304876120 |
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