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A human monoclonal antibody combination rescues nonhuman primates from advanced disease caused by the major lineages of Lassa virus

There are no approved treatments for Lassa fever (LF), which is responsible for thousands of deaths each year in West Africa. A major challenge in developing effective medical countermeasures against LF is the high diversity of circulating Lassa virus (LASV) strains with four recognized lineages and...

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Detalles Bibliográficos
Autores principales: Cross, Robert W., Heinrich, Megan L., Fenton, Karla A., Borisevich, Viktoriya, Agans, Krystle N., Prasad, Abhishek N., Woolsey, Courtney, Deer, Daniel J., Dobias, Natalie S., Rowland, Megan M., Lathigra, Raju, Borrega, Rodrigo, Geisbert, Joan B., Garry, Robert F., Branco, Luis M., Geisbert, Thomas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450431/
https://www.ncbi.nlm.nih.gov/pubmed/37590417
http://dx.doi.org/10.1073/pnas.2304876120

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