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Four-layer folding framework: design, GAP synthesis, and aggregation-induced emission
The design and synthesis of a type of [1 + 4 + 2] four-layer framework have been conducted by taking advantage of Suzuki–Miyaura cross-coupling and group-assisted purification (GAP) chemistry. The optimized coupling of double-layer diboronic esters with 1-bromo-naphth-2-yl phosphine oxides resulted...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450629/ https://www.ncbi.nlm.nih.gov/pubmed/37638105 http://dx.doi.org/10.3389/fchem.2023.1259609 |
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author | Zhang, Sai Chen, Daixiang Wang, Jia-Yin Yan, Shenghu Li, Guigen |
author_facet | Zhang, Sai Chen, Daixiang Wang, Jia-Yin Yan, Shenghu Li, Guigen |
author_sort | Zhang, Sai |
collection | PubMed |
description | The design and synthesis of a type of [1 + 4 + 2] four-layer framework have been conducted by taking advantage of Suzuki–Miyaura cross-coupling and group-assisted purification (GAP) chemistry. The optimized coupling of double-layer diboronic esters with 1-bromo-naphth-2-yl phosphine oxides resulted in a series of multilayer folding targets, showing a broad scope of substrates and moderate to excellent yields. The final products were purified using group-assisted purification chemistry/technology, achieved simply by washing crude products with 95% EtOH without the use of chromatography and recrystallization. The structures were fully characterized and assigned by performing X-ray crystallographic analysis. UV–vis absorption, photoluminescence (PL), and aggregation-induced emission (AIE) were studied for the resulting multilayer folding products. |
format | Online Article Text |
id | pubmed-10450629 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-104506292023-08-26 Four-layer folding framework: design, GAP synthesis, and aggregation-induced emission Zhang, Sai Chen, Daixiang Wang, Jia-Yin Yan, Shenghu Li, Guigen Front Chem Chemistry The design and synthesis of a type of [1 + 4 + 2] four-layer framework have been conducted by taking advantage of Suzuki–Miyaura cross-coupling and group-assisted purification (GAP) chemistry. The optimized coupling of double-layer diboronic esters with 1-bromo-naphth-2-yl phosphine oxides resulted in a series of multilayer folding targets, showing a broad scope of substrates and moderate to excellent yields. The final products were purified using group-assisted purification chemistry/technology, achieved simply by washing crude products with 95% EtOH without the use of chromatography and recrystallization. The structures were fully characterized and assigned by performing X-ray crystallographic analysis. UV–vis absorption, photoluminescence (PL), and aggregation-induced emission (AIE) were studied for the resulting multilayer folding products. Frontiers Media S.A. 2023-08-10 /pmc/articles/PMC10450629/ /pubmed/37638105 http://dx.doi.org/10.3389/fchem.2023.1259609 Text en Copyright © 2023 Zhang, Chen, Wang, Yan and Li. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Chemistry Zhang, Sai Chen, Daixiang Wang, Jia-Yin Yan, Shenghu Li, Guigen Four-layer folding framework: design, GAP synthesis, and aggregation-induced emission |
title | Four-layer folding framework: design, GAP synthesis, and aggregation-induced emission |
title_full | Four-layer folding framework: design, GAP synthesis, and aggregation-induced emission |
title_fullStr | Four-layer folding framework: design, GAP synthesis, and aggregation-induced emission |
title_full_unstemmed | Four-layer folding framework: design, GAP synthesis, and aggregation-induced emission |
title_short | Four-layer folding framework: design, GAP synthesis, and aggregation-induced emission |
title_sort | four-layer folding framework: design, gap synthesis, and aggregation-induced emission |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450629/ https://www.ncbi.nlm.nih.gov/pubmed/37638105 http://dx.doi.org/10.3389/fchem.2023.1259609 |
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