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BRCA1 heterozygosity promotes DNA damage-induced senescence in a sex-specific manner following repeated mild traumatic brain injury

Emerging evidence suggests cellular senescence, as a consequence of excess DNA damage and deficient repair, to be a driver of brain dysfunction following repeated mild traumatic brain injury (rmTBI). This study aimed to further investigate the role of deficient DNA repair, specifically BRCA1-related...

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Detalles Bibliográficos
Autores principales:	Leung, Emily, Taskina, Daria, Schwab, Nicole, Hazrati, Lili-Naz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450634/ https://www.ncbi.nlm.nih.gov/pubmed/37638313 http://dx.doi.org/10.3389/fnins.2023.1225226

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