Focused ultrasound–mediated brain genome editing

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Gene editing in the brain has been challenging because of the restricted transport imposed by the blood–brain barrier (BBB). Current approaches mainly rely on local injection to bypass the BBB. However, such administration is highly invasive and not amenable to treating certain delicate regions of t...

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Detalles Bibliográficos
Autores principales: Lao, Yeh-Hsing, Ji, Robin, Zhou, Joyce K., Snow, Kathy J., Kwon, Nancy, Saville, Ethan, He, Siyu, Chauhan, Shradha, Chi, Chun-Wei, Datta, Malika S., Zhang, Hairong, Quek, Chai Hoon, Cai, S. Sarah, Li, Mingqiang, Gaitan, Yaned, Bechtel, Lawrence, Wu, Shih-Ying, Lutz, Cathleen M., Tomer, Raju, Murray, Stephen A., Chavez, Alejandro, Konofagou, Elisa E., Leong, Kam W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450663/
https://www.ncbi.nlm.nih.gov/pubmed/37579143
http://dx.doi.org/10.1073/pnas.2302910120

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