CD44 acts as a coreceptor for cell-specific enhancement of signaling and regulatory T cell induction by TGM1, a parasite TGF-β mimic

Long-lived parasites evade host immunity through highly evolved molecular strategies. The murine intestinal helminth, Heligmosomoides polygyrus, down-modulates the host immune system through release of an immunosuppressive TGF-β mimic, TGM1, which is a divergent member of the CCP (Sushi) protein fam...

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Detalles Bibliográficos
Autores principales: van Dinther, Maarten, Cunningham, Kyle T., Singh, Shashi Prakash, White, Madeleine P. J., Campion, Tiffany, Ciancia, Claire, van Veelen, Peter A., de Ru, Arnoud H., González-Prieto, Román, Mukundan, Ananya, Byeon, Chang-Hyeock, Staggers, Sophia R., Hinck, Cynthia S., Hinck, Andrew P., Dijke, Peter ten, Maizels, Rick M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450677/
https://www.ncbi.nlm.nih.gov/pubmed/37590410
http://dx.doi.org/10.1073/pnas.2302370120

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