Effectiveness of everolimus for sporadic renal angiomyolipoma with inferior vena cava thrombus: A case report

Sporadic Renal Angiomyolipoma (AML) is commonly managed through transcatheter arterial embolization (TAE) or surgical intervention. In this report, we present a remarkable case of tumor regression from Novick Classification level 2 to level 1 in a 54-year-old male with sporadic renal AML and inferio...

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Detalles Bibliográficos
Autores principales: Iwatani, Kosuke, Miki, Jun, Urabe, Fumihiko, Yanagisawa, Takafumi, Hatano, Takashi, Kimura, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450832/
https://www.ncbi.nlm.nih.gov/pubmed/37636240
http://dx.doi.org/10.1016/j.eucr.2023.102520
Descripción
Sumario:Sporadic Renal Angiomyolipoma (AML) is commonly managed through transcatheter arterial embolization (TAE) or surgical intervention. In this report, we present a remarkable case of tumor regression from Novick Classification level 2 to level 1 in a 54-year-old male with sporadic renal AML and inferior vena cava (IVC) involvement, treated with the administration of everolimus. Subsequently, laparoscopic nephrectomy without cavectomy was performed. Notably, the patient did not present with tuberous sclerosis complex (TSC). Our findings highlight the potential of everolimus in the treatment of sporadic AML, even in cases unrelated to TSC, offering a viable alternative to invasive therapeutic approaches.

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