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Time-resolved single-cell RNAseq profiling identifies a novel Fabp5(+) subpopulation of inflammatory myeloid cells with delayed cytotoxic profile in chronic spinal cord injury
Traumatic spinal cord injuries (SCI) are a group of highly debilitating pathologies affecting thousands annually, and adversely affecting quality of life. Currently, no fully restorative therapies exist, and SCI still results in significant personal, societal and financial burdens. Inflammation play...
Autores principales: | Hamel, Regan, Peruzzotti-Jametti, Luca, Ridley, Katherine, Testa, Veronica, Yu, Bryan, Rowitch, David, Marioni, John C., Pluchino, Stefano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450865/ https://www.ncbi.nlm.nih.gov/pubmed/37636454 http://dx.doi.org/10.1016/j.heliyon.2023.e18339 |
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