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Neglected zoonotic helminthiases in wild canids: new insights from South America

The global threat of neglected tropical diseases (NTDs) constitutes a public health issue in underdeveloped countries. Zoonotic helminthiases are the most common human NTD agents in developing countries in sub-Saharan Africa, Asia, and the Americas, causing a global burden of disease that exceeds th...

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Autores principales: Uribe, Manuel, Brabec, Jan, Chaparro-Gutiérrez, Jenny J., Hermosilla, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450927/
https://www.ncbi.nlm.nih.gov/pubmed/37635759
http://dx.doi.org/10.3389/fvets.2023.1235182
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author Uribe, Manuel
Brabec, Jan
Chaparro-Gutiérrez, Jenny J.
Hermosilla, Carlos
author_facet Uribe, Manuel
Brabec, Jan
Chaparro-Gutiérrez, Jenny J.
Hermosilla, Carlos
author_sort Uribe, Manuel
collection PubMed
description The global threat of neglected tropical diseases (NTDs) constitutes a public health issue in underdeveloped countries. Zoonotic helminthiases are the most common human NTD agents in developing countries in sub-Saharan Africa, Asia, and the Americas, causing a global burden of disease that exceeds that of more recognized infectious diseases such as malaria and tuberculosis. Wild canids are well-known mammals that act as natural reservoirs of zoonotic-relevant helminthiasis worldwide, thus playing a pivotal role in their epidemiology and transmission to humans. Here we evaluate the occurrence of zoonotic gastrointestinal helminths in two Neotropical wild canid species from the Amazonian and Andean regions of Colombia, i.e., the bush dog (Speothos venaticus) and the crab-eating fox (Cerdocyon thous). We recovered tapeworm proglottids from bush dog fecal samples and identified them molecularly as the canine-specific lineage of Dipylidium caninum by using cytochrome c oxidase subunit I (cox1) gene sequences. Moreover, examination of a crab-eating fox during necropsy revealed the presence of non-embryonated eggs of the neglected nematode Lagochilascaris cf. minor, in addition to eggs and gravid proglottids of the cestode Spirometra mansoni. These findings represent the first report of zoonotic-relevant cestodes, i.e., D. caninum (“canine genotype”), S. mansoni, and the nematode L. cf. minor, in bush dogs and crab-eating foxes as final hosts. The occurrence of these zoonotic helminthiases in wild canid species calls for regular monitoring programs to better understand the epidemiology and transmission routes of neglected dipylidiasis, lagochilascariosis, and sparganosis in South America.
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spelling pubmed-104509272023-08-26 Neglected zoonotic helminthiases in wild canids: new insights from South America Uribe, Manuel Brabec, Jan Chaparro-Gutiérrez, Jenny J. Hermosilla, Carlos Front Vet Sci Veterinary Science The global threat of neglected tropical diseases (NTDs) constitutes a public health issue in underdeveloped countries. Zoonotic helminthiases are the most common human NTD agents in developing countries in sub-Saharan Africa, Asia, and the Americas, causing a global burden of disease that exceeds that of more recognized infectious diseases such as malaria and tuberculosis. Wild canids are well-known mammals that act as natural reservoirs of zoonotic-relevant helminthiasis worldwide, thus playing a pivotal role in their epidemiology and transmission to humans. Here we evaluate the occurrence of zoonotic gastrointestinal helminths in two Neotropical wild canid species from the Amazonian and Andean regions of Colombia, i.e., the bush dog (Speothos venaticus) and the crab-eating fox (Cerdocyon thous). We recovered tapeworm proglottids from bush dog fecal samples and identified them molecularly as the canine-specific lineage of Dipylidium caninum by using cytochrome c oxidase subunit I (cox1) gene sequences. Moreover, examination of a crab-eating fox during necropsy revealed the presence of non-embryonated eggs of the neglected nematode Lagochilascaris cf. minor, in addition to eggs and gravid proglottids of the cestode Spirometra mansoni. These findings represent the first report of zoonotic-relevant cestodes, i.e., D. caninum (“canine genotype”), S. mansoni, and the nematode L. cf. minor, in bush dogs and crab-eating foxes as final hosts. The occurrence of these zoonotic helminthiases in wild canid species calls for regular monitoring programs to better understand the epidemiology and transmission routes of neglected dipylidiasis, lagochilascariosis, and sparganosis in South America. Frontiers Media S.A. 2023-08-11 /pmc/articles/PMC10450927/ /pubmed/37635759 http://dx.doi.org/10.3389/fvets.2023.1235182 Text en Copyright © 2023 Uribe, Brabec, Chaparro-Gutiérrez and Hermosilla. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
Uribe, Manuel
Brabec, Jan
Chaparro-Gutiérrez, Jenny J.
Hermosilla, Carlos
Neglected zoonotic helminthiases in wild canids: new insights from South America
title Neglected zoonotic helminthiases in wild canids: new insights from South America
title_full Neglected zoonotic helminthiases in wild canids: new insights from South America
title_fullStr Neglected zoonotic helminthiases in wild canids: new insights from South America
title_full_unstemmed Neglected zoonotic helminthiases in wild canids: new insights from South America
title_short Neglected zoonotic helminthiases in wild canids: new insights from South America
title_sort neglected zoonotic helminthiases in wild canids: new insights from south america
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450927/
https://www.ncbi.nlm.nih.gov/pubmed/37635759
http://dx.doi.org/10.3389/fvets.2023.1235182
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