Drug-induced phospholipidosis is not correlated with the inhibition of SARS-CoV-2 - inhibition of SARS-CoV-2 is cell line-specific

Recently, Tummino et al. reported that 34 compounds, including Chloroquine and Fluoxetine, inhibit SARS-CoV-2 replication by inducing phospholipidosis, although Chloroquine failed to suppress viral replication in Calu-3 cells and patients. In contrast, Fluoxetine represses viral replication in human...

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Detalles Bibliográficos
Autores principales: Diesendorf, Viktoria, Roll, Valeria, Geiger, Nina, Fähr, Sofie, Obernolte, Helena, Sewald, Katherina, Bodem, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450944/
https://www.ncbi.nlm.nih.gov/pubmed/37637460
http://dx.doi.org/10.3389/fcimb.2023.1100028

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