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Gene deletion of long-chain acyl-CoA synthetase 4 attenuates xenobiotic chemical-induced lung injury via the suppression of lipid peroxidation

Long-chain acyl-CoA synthetase (ACSL) 4 converts polyunsaturated fatty acids (PUFAs) into their acyl-CoAs and plays an important role in maintaining PUFA-containing membrane phospholipids. Here we demonstrated decreases in various kinds of PUFA-containing phospholipid species in ACSL4-deficient muri...

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Detalles Bibliográficos
Autores principales:	Tomitsuka, Yuki, Imaeda, Hiroki, Ito, Haruka, Asou, Isaki, Ohbayashi, Masayuki, Ishikawa, Fumihiro, Kuwata, Hiroshi, Hara, Shuntaro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10450978/ https://www.ncbi.nlm.nih.gov/pubmed/37586249 http://dx.doi.org/10.1016/j.redox.2023.102850

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