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Hydrogel-Encapsulated Beads Enable Proximity-Driven Encoded Library Synthesis and Screening

[Image: see text] Encoded combinatorial library technologies have dramatically expanded the chemical space for screening but are usually only analyzed by affinity selection binding. It would be highly advantageous to reformat selection outputs to ”one-bead-one-compound” solid-phase libraries, unlock...

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Detalles Bibliográficos
Autores principales: Cavett, Valerie, Chan, Alix I, Cunningham, Christian N., Paegel, Brian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10451030/
https://www.ncbi.nlm.nih.gov/pubmed/37637732
http://dx.doi.org/10.1021/acscentsci.3c00316