Efficacy of mRNA-1273 and Novavax ancestral or BA.1 spike booster vaccines against SARS-CoV-2 BA.5 infection in non-human primates

Omicron SARS-CoV-2 variants escape vaccine-induced neutralizing antibodies and cause nearly all current COVID-19 cases. Here, we compared the efficacy of three booster vaccines against Omicron BA.5 challenge in rhesus macaques: mRNA-1273, the Novavax ancestral spike protein vaccine (NVX-CoV2373), or...

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Detalles Bibliográficos
Autores principales: Routhu, Nanda Kishore, Stampfer, Samuel David, Lai, Lilin, Akhtar, Akil, Tong, Xin, Yuan, Dansu, Chicz, Taras M., McNamara, Ryan P., Jakkala, Kishor, Davis-Gardner, Meredith E., St Pierre, E. Lovisa, Smith, Brandon, Green, Kristyn Moore, Golden, Nadia, Picou, Breanna, Jean, Sherrie M., Wood, Jennifer, Cohen, Joyce, Moore, Ian N., Patel, Nita, Guebre-Xabier, Mimi, Smith, Gale, Glenn, Greg, Kozlowski, Pamela A., Alter, Galit, Ahmed, Rafi, Suthar, Mehul S., Amara, Rama Rao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10451060/
https://www.ncbi.nlm.nih.gov/pubmed/37191508
http://dx.doi.org/10.1126/sciimmunol.adg7015

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