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Ret deficiency decreases neural crest progenitor proliferation and restricts fate potential during enteric nervous system development

The receptor tyrosine kinase RET plays a critical role in the fate specification of enteric neural crest–derived cells (ENCDCs) during enteric nervous system (ENS) development. RET loss of function (LoF) is associated with Hirschsprung disease (HSCR), which is marked by aganglionosis of the gastroin...

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Detalles Bibliográficos
Autores principales:	Vincent, Elizabeth, Chatterjee, Sumantra, Cannon, Gabrielle H., Auer, Dallas, Ross, Holly, Chakravarti, Aravinda, Goff, Loyal A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2023
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10451519/ https://www.ncbi.nlm.nih.gov/pubmed/37585461 http://dx.doi.org/10.1073/pnas.2211986120

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