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Exogenous CFH Modulates Levels of Pro-Inflammatory Mediators to Prevent Oxidative Damage of Retinal Pigment Epithelial Cells with the At-Risk CFH Y402H Variant
Age-related macular degeneration (AMD) is a complex, progressive degenerative retinal disease. Retinal pigment epithelial (RPE) cells play an important role in the immune defense of the eye and their dysfunction leads to the progressive irreversible degeneration of photoreceptors. Genetic factors, c...
Autores principales: | Velazquez-Soto, Henry, Groman-Lupa, Sergio, Cruz-Aguilar, Marisa, Salazar, Alberto L., Zenteno, Juan C., Jimenez-Martinez, Maria C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10451625/ https://www.ncbi.nlm.nih.gov/pubmed/37627535 http://dx.doi.org/10.3390/antiox12081540 |
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