Protein Kinase C at the Crossroad of Mutations, Cancer, Targeted Therapy and Immune Response

SIMPLE SUMMARY: This review aims to analyze the clinical drawbacks faced by PKC inhibitors and uncovering aspects that might potentially interfere with the clinical outcome of compounds targeting PKC. In-depth analyses of the impact of key PKC mutations, the failures and promises of clinical trials...

Descripción completa

Detalles Bibliográficos
Autores principales: Aquino, Angelo, Bianchi, Nicoletta, Terrazzan, Anna, Franzese, Ornella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10451643/
https://www.ncbi.nlm.nih.gov/pubmed/37626933
http://dx.doi.org/10.3390/biology12081047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10451643/
https://www.ncbi.nlm.nih.gov/pubmed/37626933
http://dx.doi.org/10.3390/biology12081047

Ejemplares similares