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Protein Kinase C at the Crossroad of Mutations, Cancer, Targeted Therapy and Immune Response
SIMPLE SUMMARY: This review aims to analyze the clinical drawbacks faced by PKC inhibitors and uncovering aspects that might potentially interfere with the clinical outcome of compounds targeting PKC. In-depth analyses of the impact of key PKC mutations, the failures and promises of clinical trials...
Autores principales: | Aquino, Angelo, Bianchi, Nicoletta, Terrazzan, Anna, Franzese, Ornella |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10451643/ https://www.ncbi.nlm.nih.gov/pubmed/37626933 http://dx.doi.org/10.3390/biology12081047 |
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