Cargando…

Physical Activity as a Modern Intervention in the Fight against Obesity-Related Inflammation in Type 2 Diabetes Mellitus and Gestational Diabetes

Diabetes is one of the greatest healthcare problems; it requires an appropriate approach to the patient, especially when it concerns pregnant women. Gestational diabetes mellitus (GDM) is a common metabolic condition in pregnancy that shares many features with type 2 diabetes mellitus (T2DM). T2DM a...

Descripción completa

Detalles Bibliográficos
Autores principales: Piotrowska, Katarzyna, Zgutka, Katarzyna, Tkacz, Marta, Tarnowski, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10451679/
https://www.ncbi.nlm.nih.gov/pubmed/37627482
http://dx.doi.org/10.3390/antiox12081488
_version_ 1785095475084394496
author Piotrowska, Katarzyna
Zgutka, Katarzyna
Tkacz, Marta
Tarnowski, Maciej
author_facet Piotrowska, Katarzyna
Zgutka, Katarzyna
Tkacz, Marta
Tarnowski, Maciej
author_sort Piotrowska, Katarzyna
collection PubMed
description Diabetes is one of the greatest healthcare problems; it requires an appropriate approach to the patient, especially when it concerns pregnant women. Gestational diabetes mellitus (GDM) is a common metabolic condition in pregnancy that shares many features with type 2 diabetes mellitus (T2DM). T2DM and GDM induce oxidative stress, which activates cellular stress signalling. In addition, the risk of diabetes during pregnancy can lead to various complications for the mother and foetus. It has been shown that physical activity is an important tool to not only treat the negative effects of diabetes but also to prevent its progression or even reverse the changes already made by limiting the inflammatory process. Physical activity has a huge impact on the immune status of an individual. Various studies have shown that regular training sessions cause changes in circulating immune cell levels, cytokine activation, production and secretion and changes in microRNA, all of which have a positive effect on the well-being of the diabetic patient, mother and foetus.
format Online
Article
Text
id pubmed-10451679
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-104516792023-08-26 Physical Activity as a Modern Intervention in the Fight against Obesity-Related Inflammation in Type 2 Diabetes Mellitus and Gestational Diabetes Piotrowska, Katarzyna Zgutka, Katarzyna Tkacz, Marta Tarnowski, Maciej Antioxidants (Basel) Review Diabetes is one of the greatest healthcare problems; it requires an appropriate approach to the patient, especially when it concerns pregnant women. Gestational diabetes mellitus (GDM) is a common metabolic condition in pregnancy that shares many features with type 2 diabetes mellitus (T2DM). T2DM and GDM induce oxidative stress, which activates cellular stress signalling. In addition, the risk of diabetes during pregnancy can lead to various complications for the mother and foetus. It has been shown that physical activity is an important tool to not only treat the negative effects of diabetes but also to prevent its progression or even reverse the changes already made by limiting the inflammatory process. Physical activity has a huge impact on the immune status of an individual. Various studies have shown that regular training sessions cause changes in circulating immune cell levels, cytokine activation, production and secretion and changes in microRNA, all of which have a positive effect on the well-being of the diabetic patient, mother and foetus. MDPI 2023-07-25 /pmc/articles/PMC10451679/ /pubmed/37627482 http://dx.doi.org/10.3390/antiox12081488 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Piotrowska, Katarzyna
Zgutka, Katarzyna
Tkacz, Marta
Tarnowski, Maciej
Physical Activity as a Modern Intervention in the Fight against Obesity-Related Inflammation in Type 2 Diabetes Mellitus and Gestational Diabetes
title Physical Activity as a Modern Intervention in the Fight against Obesity-Related Inflammation in Type 2 Diabetes Mellitus and Gestational Diabetes
title_full Physical Activity as a Modern Intervention in the Fight against Obesity-Related Inflammation in Type 2 Diabetes Mellitus and Gestational Diabetes
title_fullStr Physical Activity as a Modern Intervention in the Fight against Obesity-Related Inflammation in Type 2 Diabetes Mellitus and Gestational Diabetes
title_full_unstemmed Physical Activity as a Modern Intervention in the Fight against Obesity-Related Inflammation in Type 2 Diabetes Mellitus and Gestational Diabetes
title_short Physical Activity as a Modern Intervention in the Fight against Obesity-Related Inflammation in Type 2 Diabetes Mellitus and Gestational Diabetes
title_sort physical activity as a modern intervention in the fight against obesity-related inflammation in type 2 diabetes mellitus and gestational diabetes
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10451679/
https://www.ncbi.nlm.nih.gov/pubmed/37627482
http://dx.doi.org/10.3390/antiox12081488
work_keys_str_mv AT piotrowskakatarzyna physicalactivityasamoderninterventioninthefightagainstobesityrelatedinflammationintype2diabetesmellitusandgestationaldiabetes
AT zgutkakatarzyna physicalactivityasamoderninterventioninthefightagainstobesityrelatedinflammationintype2diabetesmellitusandgestationaldiabetes
AT tkaczmarta physicalactivityasamoderninterventioninthefightagainstobesityrelatedinflammationintype2diabetesmellitusandgestationaldiabetes
AT tarnowskimaciej physicalactivityasamoderninterventioninthefightagainstobesityrelatedinflammationintype2diabetesmellitusandgestationaldiabetes