Cargando…

An Approach to Binary Classification of Alzheimer’s Disease Using LSTM

In this study, we use LSTM (Long-Short-Term-Memory) networks to evaluate Magnetic Resonance Imaging (MRI) data to overcome the shortcomings of conventional Alzheimer’s disease (AD) detection techniques. Our method offers greater reliability and accuracy in predicting the possibility of AD, in contra...

Descripción completa

Detalles Bibliográficos
Autores principales: Salehi, Waleed, Baglat, Preety, Gupta, Gaurav, Khan, Surbhi Bhatia, Almusharraf, Ahlam, Alqahtani, Ali, Kumar, Adarsh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10451729/
https://www.ncbi.nlm.nih.gov/pubmed/37627835
http://dx.doi.org/10.3390/bioengineering10080950
_version_ 1785095488509313024
author Salehi, Waleed
Baglat, Preety
Gupta, Gaurav
Khan, Surbhi Bhatia
Almusharraf, Ahlam
Alqahtani, Ali
Kumar, Adarsh
author_facet Salehi, Waleed
Baglat, Preety
Gupta, Gaurav
Khan, Surbhi Bhatia
Almusharraf, Ahlam
Alqahtani, Ali
Kumar, Adarsh
author_sort Salehi, Waleed
collection PubMed
description In this study, we use LSTM (Long-Short-Term-Memory) networks to evaluate Magnetic Resonance Imaging (MRI) data to overcome the shortcomings of conventional Alzheimer’s disease (AD) detection techniques. Our method offers greater reliability and accuracy in predicting the possibility of AD, in contrast to cognitive testing and brain structure analyses. We used an MRI dataset that we downloaded from the Kaggle source to train our LSTM network. Utilizing the temporal memory characteristics of LSTMs, the network was created to efficiently capture and evaluate the sequential patterns inherent in MRI scans. Our model scored a remarkable AUC of 0.97 and an accuracy of 98.62%. During the training process, we used Stratified Shuffle-Split Cross Validation to make sure that our findings were reliable and generalizable. Our study adds significantly to the body of knowledge by demonstrating the potential of LSTM networks in the specific field of AD prediction and extending the variety of methods investigated for image classification in AD research. We have also designed a user-friendly Web-based application to help with the accessibility of our developed model, bridging the gap between research and actual deployment.
format Online
Article
Text
id pubmed-10451729
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-104517292023-08-26 An Approach to Binary Classification of Alzheimer’s Disease Using LSTM Salehi, Waleed Baglat, Preety Gupta, Gaurav Khan, Surbhi Bhatia Almusharraf, Ahlam Alqahtani, Ali Kumar, Adarsh Bioengineering (Basel) Article In this study, we use LSTM (Long-Short-Term-Memory) networks to evaluate Magnetic Resonance Imaging (MRI) data to overcome the shortcomings of conventional Alzheimer’s disease (AD) detection techniques. Our method offers greater reliability and accuracy in predicting the possibility of AD, in contrast to cognitive testing and brain structure analyses. We used an MRI dataset that we downloaded from the Kaggle source to train our LSTM network. Utilizing the temporal memory characteristics of LSTMs, the network was created to efficiently capture and evaluate the sequential patterns inherent in MRI scans. Our model scored a remarkable AUC of 0.97 and an accuracy of 98.62%. During the training process, we used Stratified Shuffle-Split Cross Validation to make sure that our findings were reliable and generalizable. Our study adds significantly to the body of knowledge by demonstrating the potential of LSTM networks in the specific field of AD prediction and extending the variety of methods investigated for image classification in AD research. We have also designed a user-friendly Web-based application to help with the accessibility of our developed model, bridging the gap between research and actual deployment. MDPI 2023-08-09 /pmc/articles/PMC10451729/ /pubmed/37627835 http://dx.doi.org/10.3390/bioengineering10080950 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Salehi, Waleed
Baglat, Preety
Gupta, Gaurav
Khan, Surbhi Bhatia
Almusharraf, Ahlam
Alqahtani, Ali
Kumar, Adarsh
An Approach to Binary Classification of Alzheimer’s Disease Using LSTM
title An Approach to Binary Classification of Alzheimer’s Disease Using LSTM
title_full An Approach to Binary Classification of Alzheimer’s Disease Using LSTM
title_fullStr An Approach to Binary Classification of Alzheimer’s Disease Using LSTM
title_full_unstemmed An Approach to Binary Classification of Alzheimer’s Disease Using LSTM
title_short An Approach to Binary Classification of Alzheimer’s Disease Using LSTM
title_sort approach to binary classification of alzheimer’s disease using lstm
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10451729/
https://www.ncbi.nlm.nih.gov/pubmed/37627835
http://dx.doi.org/10.3390/bioengineering10080950
work_keys_str_mv AT salehiwaleed anapproachtobinaryclassificationofalzheimersdiseaseusinglstm
AT baglatpreety anapproachtobinaryclassificationofalzheimersdiseaseusinglstm
AT guptagaurav anapproachtobinaryclassificationofalzheimersdiseaseusinglstm
AT khansurbhibhatia anapproachtobinaryclassificationofalzheimersdiseaseusinglstm
AT almusharrafahlam anapproachtobinaryclassificationofalzheimersdiseaseusinglstm
AT alqahtaniali anapproachtobinaryclassificationofalzheimersdiseaseusinglstm
AT kumaradarsh anapproachtobinaryclassificationofalzheimersdiseaseusinglstm
AT salehiwaleed approachtobinaryclassificationofalzheimersdiseaseusinglstm
AT baglatpreety approachtobinaryclassificationofalzheimersdiseaseusinglstm
AT guptagaurav approachtobinaryclassificationofalzheimersdiseaseusinglstm
AT khansurbhibhatia approachtobinaryclassificationofalzheimersdiseaseusinglstm
AT almusharrafahlam approachtobinaryclassificationofalzheimersdiseaseusinglstm
AT alqahtaniali approachtobinaryclassificationofalzheimersdiseaseusinglstm
AT kumaradarsh approachtobinaryclassificationofalzheimersdiseaseusinglstm