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An Approach to Binary Classification of Alzheimer’s Disease Using LSTM
In this study, we use LSTM (Long-Short-Term-Memory) networks to evaluate Magnetic Resonance Imaging (MRI) data to overcome the shortcomings of conventional Alzheimer’s disease (AD) detection techniques. Our method offers greater reliability and accuracy in predicting the possibility of AD, in contra...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10451729/ https://www.ncbi.nlm.nih.gov/pubmed/37627835 http://dx.doi.org/10.3390/bioengineering10080950 |
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author | Salehi, Waleed Baglat, Preety Gupta, Gaurav Khan, Surbhi Bhatia Almusharraf, Ahlam Alqahtani, Ali Kumar, Adarsh |
author_facet | Salehi, Waleed Baglat, Preety Gupta, Gaurav Khan, Surbhi Bhatia Almusharraf, Ahlam Alqahtani, Ali Kumar, Adarsh |
author_sort | Salehi, Waleed |
collection | PubMed |
description | In this study, we use LSTM (Long-Short-Term-Memory) networks to evaluate Magnetic Resonance Imaging (MRI) data to overcome the shortcomings of conventional Alzheimer’s disease (AD) detection techniques. Our method offers greater reliability and accuracy in predicting the possibility of AD, in contrast to cognitive testing and brain structure analyses. We used an MRI dataset that we downloaded from the Kaggle source to train our LSTM network. Utilizing the temporal memory characteristics of LSTMs, the network was created to efficiently capture and evaluate the sequential patterns inherent in MRI scans. Our model scored a remarkable AUC of 0.97 and an accuracy of 98.62%. During the training process, we used Stratified Shuffle-Split Cross Validation to make sure that our findings were reliable and generalizable. Our study adds significantly to the body of knowledge by demonstrating the potential of LSTM networks in the specific field of AD prediction and extending the variety of methods investigated for image classification in AD research. We have also designed a user-friendly Web-based application to help with the accessibility of our developed model, bridging the gap between research and actual deployment. |
format | Online Article Text |
id | pubmed-10451729 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-104517292023-08-26 An Approach to Binary Classification of Alzheimer’s Disease Using LSTM Salehi, Waleed Baglat, Preety Gupta, Gaurav Khan, Surbhi Bhatia Almusharraf, Ahlam Alqahtani, Ali Kumar, Adarsh Bioengineering (Basel) Article In this study, we use LSTM (Long-Short-Term-Memory) networks to evaluate Magnetic Resonance Imaging (MRI) data to overcome the shortcomings of conventional Alzheimer’s disease (AD) detection techniques. Our method offers greater reliability and accuracy in predicting the possibility of AD, in contrast to cognitive testing and brain structure analyses. We used an MRI dataset that we downloaded from the Kaggle source to train our LSTM network. Utilizing the temporal memory characteristics of LSTMs, the network was created to efficiently capture and evaluate the sequential patterns inherent in MRI scans. Our model scored a remarkable AUC of 0.97 and an accuracy of 98.62%. During the training process, we used Stratified Shuffle-Split Cross Validation to make sure that our findings were reliable and generalizable. Our study adds significantly to the body of knowledge by demonstrating the potential of LSTM networks in the specific field of AD prediction and extending the variety of methods investigated for image classification in AD research. We have also designed a user-friendly Web-based application to help with the accessibility of our developed model, bridging the gap between research and actual deployment. MDPI 2023-08-09 /pmc/articles/PMC10451729/ /pubmed/37627835 http://dx.doi.org/10.3390/bioengineering10080950 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Salehi, Waleed Baglat, Preety Gupta, Gaurav Khan, Surbhi Bhatia Almusharraf, Ahlam Alqahtani, Ali Kumar, Adarsh An Approach to Binary Classification of Alzheimer’s Disease Using LSTM |
title | An Approach to Binary Classification of Alzheimer’s Disease Using LSTM |
title_full | An Approach to Binary Classification of Alzheimer’s Disease Using LSTM |
title_fullStr | An Approach to Binary Classification of Alzheimer’s Disease Using LSTM |
title_full_unstemmed | An Approach to Binary Classification of Alzheimer’s Disease Using LSTM |
title_short | An Approach to Binary Classification of Alzheimer’s Disease Using LSTM |
title_sort | approach to binary classification of alzheimer’s disease using lstm |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10451729/ https://www.ncbi.nlm.nih.gov/pubmed/37627835 http://dx.doi.org/10.3390/bioengineering10080950 |
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