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Mitochondrial Reactive Oxygen Species Formation Determines ACSL4/LPCAT2-Mediated Ferroptosis

Ferroptosis is a form of oxidative cell death that is characterized by enhanced lipid peroxidation and mitochondrial impairment. The enzymes acyl-CoA synthetase long-chain family member 4 (ACSL4) and lysophosphatidylcholine acyltransferase (LPCAT) play an essential role in the biosynthesis of polyun...

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Detalles Bibliográficos
Autores principales:	Merkel, Melanie, Goebel, Bjarne, Boll, Moritz, Adhikari, Aasha, Maurer, Viktoria, Steinhilber, Dieter, Culmsee, Carsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10451816/ https://www.ncbi.nlm.nih.gov/pubmed/37627584 http://dx.doi.org/10.3390/antiox12081590

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