Cargando…

Nitroxide—HMP—Protects Human Trophoblast HTR-8/SVneo Cells from H(2)O(2)-Induced Oxidative Stress by Reducing the HIF1A Signaling Pathway

Preeclampsia (PE) is a pregnancy-specific syndrome affecting 5–7% of patients. There is no effective treatment available. Early abnormal placental development is associated with oxidative stress (OS) and a release of reactive oxygen species (ROS) in the placenta. This phenomenon leads to downstream...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pintye, Diana, Sziva, Réka Eszter, Mastyugin, Maxim, Török, Marianna, Jacas, Sonako, Lo, Agnes, Salahuddin, Saira, Zsengellér, Zsuzsanna K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10451835/ https://www.ncbi.nlm.nih.gov/pubmed/37627573 http://dx.doi.org/10.3390/antiox12081578

Ejemplares similares

A Novel Dual-Function Redox Modulator Relieves Oxidative Stress and Anti-Angiogenic Response in Placental Villus Explant Exposed to Hypoxia—Relevance for Preeclampsia Therapy
por: Pintye, Diana, et al.
Publicado: (2023)

Serum depletion induces changes in protein expression in the trophoblast-derived cell line HTR-8/SVneo
por: Novoa-Herran, Susana, et al.
Publicado: (2016)

Hepatocyte growth factor regulates HLX1 gene expression to modulate HTR-8/SVneo trophoblast cells
por: Liu, Hai-Ying, et al.
Publicado: (2012)

GABA A receptor π subunit promotes apoptosis of HTR-8/SVneo trophoblastic cells: Implications in preeclampsia
por: LU, JUNJIE, et al.
Publicado: (2016)

BMP9 maintains the phenotype of HTR-8/Svneo trophoblast cells by activating the SDF1/CXCR4 pathway
por: Yang, Xue, et al.
Publicado: (2023)

Isolation and Characterization of Human Trophoblast Side-Population (SP) Cells in Primary Villous Cytotrophoblasts and HTR-8/SVneo Cell Line
por: Takao, Tomoka, et al.
Publicado: (2011)

Delta-9-tetrahydrocannabinol inhibits invasion of HTR8/SVneo human extravillous trophoblast cells and negatively impacts mitochondrial function
por: Walker, O’Llenecia S., et al.
Publicado: (2021)

Lycium barbarum polysaccharides protect human trophoblast HTR8/SVneo cells from hydrogen peroxide-induced oxidative stress and apoptosis
por: Li, Jing, et al.
Publicado: (2018)

MicroRNA-524-5p regulates the proliferation and invasion of HTR-8/SVneo trophoblasts by targeting NUMB in the Notch signaling pathway
por: Zheng, Linmei, et al.
Publicado: (2021)

Psoralen Promotes Proliferation, Migration, and Invasion of Human Extravillous Trophoblast Derived HTR-8/Svneo Cells in vitro by NF-κB Pathway
por: Qi, Dan, et al.
Publicado: (2022)

Reduction in CgA-Derived CST Protein Level in HTR-8/SVneo and BeWo Trophoblastic Cell Lines Caused by the Preeclamptic Environment
por: Bralewska, Michalina, et al.
Publicado: (2023)

Valproate, thalidomide and ethyl alcohol alter the migration of HTR-8/SVneo cells
por: Rout, Ujjwal K
Publicado: (2006)

miR-183-5p suppressed the invasion and migration of HTR-8/SVneo trophoblast cells partly via targeting MMP-9 in preeclampsia
por: Suo, Mingli, et al.
Publicado: (2020)

miR-17-5p Promotes Glucose Uptake of HTR8/SVneo Trophoblast Cells by Inhibiting TXNIP/NLRP3 Inflammasome Pathway
por: Jiang, Yi, et al.
Publicado: (2022)

Exposure to environmental bisphenol A inhibits HTR-8/SVneo cell migration and invasion
por: Wei, Pu, et al.
Publicado: (2020)

Metabolic disparities of different oxidative stress-inducing conditions in HTR8/SVneo cells
por: Chen, Jingdong, et al.
Publicado: (2020)

Blocking Epidermal Growth Factor Receptor Signaling in HTR-8/SVneo First Trimester Trophoblast Cells Results in Dephosphorylation of PKBα/AKT and Induces Apoptosis
por: Bolnick, J., et al.
Publicado: (2011)

AP-1 Transcription Factors, Mucin-Type Molecules and MMPs Regulate the IL-11 Mediated Invasiveness of JEG-3 and HTR-8/SVneo Trophoblastic Cells
por: Suman, Pankaj, et al.
Publicado: (2012)

HTR8/SVneo Cells Display Trophoblast Progenitor Cell-Like Characteristics Indicative of Self-Renewal, Repopulation Activity, and Expression of “Stemness-” Associated Transcription Factors
por: Weber, Maja, et al.
Publicado: (2013)

Reactive Oxygen Stimulation of Interleukin-6 Release in the Human Trophoblast Cell Line HTR-8/SVneo by the Trichlorethylene Metabolite S-(1,2-Dichloro)-l-Cysteine
por: Hassan, Iman, et al.
Publicado: (2016)

The Preeclamptic Environment Promotes the Activation of Transcription Factor Kappa B by P53/RSK1 Complex in a HTR8/SVneo Trophoblastic Cell Line
por: Sakowicz, Agata, et al.
Publicado: (2021)

Hyperin promotes proliferation, migration, and invasion of HTR-8/SVneo trophoblast cells via activation of JAK1/STAT3 pathway in recurrent spontaneous abortions
por: Mu, Zhenni, et al.
Publicado: (2023)

Autophagy in the HTR-8/SVneo Cell Oxidative Stress Model Is Associated with the NLRP1 Inflammasome
por: Li, Meihe, et al.
Publicado: (2021)

A Small Physiological Electric Field Mediated Responses of Extravillous Trophoblasts Derived from HTR8/SVneo Cells: Involvement of Activation of Focal Adhesion Kinase Signaling
por: Zhang, Juan, et al.
Publicado: (2014)

Increased Toxoplasma gondii Intracellular Proliferation in Human Extravillous Trophoblast Cells (HTR8/SVneo Line) Is Sequentially Triggered by MIF, ERK1/2, and COX-2
por: Milian, Iliana Claudia Balga, et al.
Publicado: (2019)

Curcumin Protects Human Trophoblast HTR8/SVneo Cells from H(2)O(2)-Induced Oxidative Stress by Activating Nrf2 Signaling Pathway
por: Qi, Lina, et al.
Publicado: (2020)

circRNA circ_0055724 Inhibits Trophoblastic Cell Line HTR-8/SVneo's Invasive and Migratory Abilities via the miR-136/N-Cadherin Axis
por: Xu, Xiaohong, et al.
Publicado: (2022)

Small GTP‐binding protein Rap1 mediates EGF and HB‐EGF signaling and modulates EGF receptor expression in HTR‐8/SVneo extravillous trophoblast cells
por: Yoshie, Mikihiro, et al.
Publicado: (2023)

Effects of transforming growth factor-β1 on the proliferation and invasion of the HTR-8/SVneo cell line
por: ZUO, YANZHEN, et al.
Publicado: (2014)

Hydrogen sulfide against preeclampsia exposure-induced oxidative mitochondrial damage in HTR-8/SVneo cells
por: Wang, Xianli, et al.
Publicado: (2022)

Adenosine A(3) Receptor Mediates ERK1/2- and JNK-Dependent TNF-α Production in Toxoplasma gondii-Infected HTR8/SVneo Human Extravillous Trophoblast Cells
por: Ye, Wei, et al.
Publicado: (2020)

IGFBP-4 and −5 are expressed in first-trimester villi and differentially regulate the migration of HTR-8/SVneo cells
por: Crosley, Erin J, et al.
Publicado: (2014)

Interdependence of JAK-STAT and MAPK signaling pathways during EGF-mediated HTR-8/SVneo cell invasion
por: Malik, Ankita, et al.
Publicado: (2017)

HMP : hoja de respuestas : habilidades mentales primarias : intermedio
por: Thurstone, L. L. (Louis Leon), 1887-1955
Publicado: (1990)

Bidirectional regulation between 1st trimester HTR8/SVneo trophoblast cells and in vitro differentiated Th17/Treg cells suggest a fetal‐maternal regulatory loop in human pregnancy
por: Wang, Songcun, et al.
Publicado: (2019)

CTGF expression is up-regulated by PROK1 in early pregnancy and influences HTR-8/Svneo cell adhesion and network formation
por: Waddell, Jennifer M., et al.
Publicado: (2011)

Upregulated unique long 16 binding protein 1 detected in preeclamptic placenta affects human extravillous trophoblast cell line (HTR-8/SVneo) invasion by modulating the function of uterine natural killer cells
por: Liu, Jing, et al.
Publicado: (2017)

Structural Features of Small Molecule Antioxidants and Strategic Modifications to Improve Potential Bioactivity
por: Charlton, Nathan C., et al.
Publicado: (2023)

HOXD8/DIAPH2-AS1 epigenetically regulates PAX3 and impairs HTR-8/SVneo cell function under hypoxia
por: Feng, Yaling, et al.
Publicado: (2019)

Identification of LncRNA-miRNA-mRNA ceRNA network in hypoxia-induced HTR-8/SVneo cells for preeclampsia
por: Liu, Zhenzhen, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_81f3j96c4pg2fn47ku488qaora