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3D Culture and Interferon-γ Priming Modulates Characteristics of Mesenchymal Stromal/Stem Cells by Modifying the Expression of Both Intracellular and Exosomal microRNAs

SIMPLE SUMMARY: With the aim of improving the therapeutic potential of mesenchymal stromal/stem cells (MSCs), we analyzed miRNA expression to investigate the effects of priming on intracellular and exosome (EXO)-derived miRNAs of MSCs. We primed MSCs with 3D culture (3D MSCs) or IFN-γ treatment (γ-M...

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Detalles Bibliográficos
Autores principales: Bulati, Matteo, Gallo, Alessia, Zito, Giovanni, Busà, Rosalia, Iannolo, Gioacchin, Cuscino, Nicola, Castelbuono, Salvatore, Carcione, Claudia, Centi, Claudio, Martucci, Gennaro, Bertani, Alessandro, Baiamonte, Maria Pia, Chinnici, Cinzia Maria, Conaldi, Pier Giulio, Miceli, Vitale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10451847/
https://www.ncbi.nlm.nih.gov/pubmed/37626949
http://dx.doi.org/10.3390/biology12081063