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Characterization of the Ang/Tie2 Signaling Pathway in the Diaphragm Muscle of DMD Mice
In Duchenne muscular dystrophy (DMD), angiogenesis appears to be attenuated. Local administration of angiopoietin 1 (Ang1) has been shown to reduce inflammation, ischemia, and fibrosis in DMD mice. Ang1 is a vital vascular stabilizing factor that activates the endothelial cell receptor Tie2, leading...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452261/ https://www.ncbi.nlm.nih.gov/pubmed/37626761 http://dx.doi.org/10.3390/biomedicines11082265 |