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Characterization of the Ang/Tie2 Signaling Pathway in the Diaphragm Muscle of DMD Mice

In Duchenne muscular dystrophy (DMD), angiogenesis appears to be attenuated. Local administration of angiopoietin 1 (Ang1) has been shown to reduce inflammation, ischemia, and fibrosis in DMD mice. Ang1 is a vital vascular stabilizing factor that activates the endothelial cell receptor Tie2, leading...

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Detalles Bibliográficos
Autores principales: Lin, Yiming, McClennan, Andrew, Hoffman, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452261/
https://www.ncbi.nlm.nih.gov/pubmed/37626761
http://dx.doi.org/10.3390/biomedicines11082265