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Embolisation Using Microvascular Plugs for Peripheral Applications: Technical Results and Mid-Term Outcomes

The Micro Vascular Plug(®) (MVP, Medtronic) is a mechanical embolic agent available in small sizes that allows for distal embolisation. The objective of this retrospective observational single-centre study was to assess MVP embolisation procedures performed at a university hospital. The 33 patients...

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Autores principales: Mailli, Rémy, Chevallier, Olivier, Mazit, Amin, Malakhia, Alexandre, Falvo, Nicolas, Loffroy, Romaric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452264/
https://www.ncbi.nlm.nih.gov/pubmed/37626671
http://dx.doi.org/10.3390/biomedicines11082172
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author Mailli, Rémy
Chevallier, Olivier
Mazit, Amin
Malakhia, Alexandre
Falvo, Nicolas
Loffroy, Romaric
author_facet Mailli, Rémy
Chevallier, Olivier
Mazit, Amin
Malakhia, Alexandre
Falvo, Nicolas
Loffroy, Romaric
author_sort Mailli, Rémy
collection PubMed
description The Micro Vascular Plug(®) (MVP, Medtronic) is a mechanical embolic agent available in small sizes that allows for distal embolisation. The objective of this retrospective observational single-centre study was to assess MVP embolisation procedures performed at a university hospital. The 33 patients who underwent MVP embolisation in 2021 were included (mean age, 64; 24 males and 9 females). The primary endpoint was technical success, which was defined as a full first-attempt occlusion with one or more MVPs, as documented on the end-of-procedure angiogram. In all patients, 51 MVPs were used overall, with other embolic agents in 23 of the 33 cases (usually coils and/or glue); 22 of the 33 procedures were emergent for bleeding and 11 were planned for other indications. Of the three technical failures, two were due to an angled target artery configuration precluding microcatheterisation and one to failure of the device to release from its wire. The technical success rate was thus 90.9%. No patient experienced MVP migration or other major complications. Five patients had recurrent clinical symptoms; in four cases, the cause was collateral development, and in one case, the cause was incomplete initial embolisation. No instances of recanalisation were documented during the short follow-up of 12 months, for a 100% secondary clinical success rate. At our tertiary-level centre, the MVP was both effective and safe for peripheral applications. Interventional radiologists should be conversant with the techniques and indications of MVP embolisation.
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spelling pubmed-104522642023-08-26 Embolisation Using Microvascular Plugs for Peripheral Applications: Technical Results and Mid-Term Outcomes Mailli, Rémy Chevallier, Olivier Mazit, Amin Malakhia, Alexandre Falvo, Nicolas Loffroy, Romaric Biomedicines Article The Micro Vascular Plug(®) (MVP, Medtronic) is a mechanical embolic agent available in small sizes that allows for distal embolisation. The objective of this retrospective observational single-centre study was to assess MVP embolisation procedures performed at a university hospital. The 33 patients who underwent MVP embolisation in 2021 were included (mean age, 64; 24 males and 9 females). The primary endpoint was technical success, which was defined as a full first-attempt occlusion with one or more MVPs, as documented on the end-of-procedure angiogram. In all patients, 51 MVPs were used overall, with other embolic agents in 23 of the 33 cases (usually coils and/or glue); 22 of the 33 procedures were emergent for bleeding and 11 were planned for other indications. Of the three technical failures, two were due to an angled target artery configuration precluding microcatheterisation and one to failure of the device to release from its wire. The technical success rate was thus 90.9%. No patient experienced MVP migration or other major complications. Five patients had recurrent clinical symptoms; in four cases, the cause was collateral development, and in one case, the cause was incomplete initial embolisation. No instances of recanalisation were documented during the short follow-up of 12 months, for a 100% secondary clinical success rate. At our tertiary-level centre, the MVP was both effective and safe for peripheral applications. Interventional radiologists should be conversant with the techniques and indications of MVP embolisation. MDPI 2023-08-02 /pmc/articles/PMC10452264/ /pubmed/37626671 http://dx.doi.org/10.3390/biomedicines11082172 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Mailli, Rémy
Chevallier, Olivier
Mazit, Amin
Malakhia, Alexandre
Falvo, Nicolas
Loffroy, Romaric
Embolisation Using Microvascular Plugs for Peripheral Applications: Technical Results and Mid-Term Outcomes
title Embolisation Using Microvascular Plugs for Peripheral Applications: Technical Results and Mid-Term Outcomes
title_full Embolisation Using Microvascular Plugs for Peripheral Applications: Technical Results and Mid-Term Outcomes
title_fullStr Embolisation Using Microvascular Plugs for Peripheral Applications: Technical Results and Mid-Term Outcomes
title_full_unstemmed Embolisation Using Microvascular Plugs for Peripheral Applications: Technical Results and Mid-Term Outcomes
title_short Embolisation Using Microvascular Plugs for Peripheral Applications: Technical Results and Mid-Term Outcomes
title_sort embolisation using microvascular plugs for peripheral applications: technical results and mid-term outcomes
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452264/
https://www.ncbi.nlm.nih.gov/pubmed/37626671
http://dx.doi.org/10.3390/biomedicines11082172
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