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New Series of Zaxinone Mimics (MiZax) for Fundamental and Applied Research

The apocarotenoid zaxinone is a recently discovered regulatory metabolite required for proper rice growth and development. In addition, zaxinone and its two mimics (MiZax3 and MiZax5) were shown to have a remarkable growth-promoting activity on crops and a capability to reduce infestation by the roo...

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Detalles Bibliográficos
Autores principales: Jamil, Muhammad, Lin, Pei-Yu, Berqdar, Lamis, Wang, Jian You, Takahashi, Ikuo, Ota, Tsuyoshi, Alhammad, Noor, Chen, Guan-Ting Erica, Asami, Tadao, Al-Babili, Salim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452442/
https://www.ncbi.nlm.nih.gov/pubmed/37627271
http://dx.doi.org/10.3390/biom13081206
Descripción
Sumario:The apocarotenoid zaxinone is a recently discovered regulatory metabolite required for proper rice growth and development. In addition, zaxinone and its two mimics (MiZax3 and MiZax5) were shown to have a remarkable growth-promoting activity on crops and a capability to reduce infestation by the root parasitic plant Striga through decreasing strigolactone (SL) production, suggesting their potential for application in agriculture and horticulture. In the present study, we developed a new series of MiZax via structural modification of the two potent zaxinone mimics (MiZax3 and MiZax5) and evaluated their effect on plant growth and Striga infestation. In general, the structural modifications to MiZax3 and MiZax5 did not additionally improve their overall performance but caused an increase in certain activities. In conclusion, MiZax5 and especially MiZax3 remain the likely most efficient zaxinone mimics for controlling Striga infestation.