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Cell Surface B2m-Free Human Leukocyte Antigen (HLA) Monomers and Dimers: Are They Neo-HLA Class and Proto-HLA?

Cell surface HLA-I molecules (Face-1) consist of a polypeptide heavy chain (HC) with two groove domains (G domain) and one constant domain (C-domain) as well as a light chain, B2-microglobulin (B2m). However, HCs can also independently emerge unfolded on the cell surface without peptides as B2m-free...

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Detalles Bibliográficos
Autores principales:	Ravindranath, Mepur H., Ravindranath, Narendranath M., Selvan, Senthamil R., Hilali, Fatiha El, Amato-Menker, Carly J., Filippone, Edward J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452486/ https://www.ncbi.nlm.nih.gov/pubmed/37627243 http://dx.doi.org/10.3390/biom13081178

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