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IGF/mTORC1/S6 Signaling Is Potentiated and Prolonged by Acute Loading of Subtoxicological Manganese Ion
The insulin-like growth factor (IGF)/insulin signaling (IIS) pathway is involved in cellular responses against intracellular divalent manganese ion (Mn(2+)) accumulation. As a pathway where multiple nodes utilize Mn(2+) as a metallic co-factor, how the IIS signaling patterns are affected by Mn(2+) o...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452562/ https://www.ncbi.nlm.nih.gov/pubmed/37627294 http://dx.doi.org/10.3390/biom13081229 |