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RET-Altered Cancers—A Tumor-Agnostic Review of Biology, Diagnosis and Targeted Therapy Activity

SIMPLE SUMMARY: Changes in the RET gene (like mutations or fusions) are often found in lung and thyroid cancers but are also found in other cancer types. New drugs called “selective RET inhibitors”, like selpercatinib and pralsetinib, are effective in treating tumors with RET gene changes. These dru...

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Detalles Bibliográficos
Autores principales: Desilets, Antoine, Repetto, Matteo, Yang, Soo-Ryum, Sherman, Eric J., Drilon, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452615/
https://www.ncbi.nlm.nih.gov/pubmed/37627175
http://dx.doi.org/10.3390/cancers15164146

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