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Effect of Leflunomide–Metal Complexes on ROS, TNF, and Brain Indolamines in Comparison with Anti-Depressants as Adjunct Therapy in Rheumatoid Arthritic Model

Leflunomide is an isoxazole immunomodulating drug used to treat rheumatoid arthritis (RA). It is adopted as a metal-containing molecule to proceed with saturated salts of essential and detected metals; it amends the pharmacokinetic and pharmacodynamics activity of leflunomide to provide [M(Lef)(4)]X...

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Detalles Bibliográficos
Autores principales: Naeem, Almas, Jahan, Noor, Khan, Moona Mehboob, Abbas, Ghulam, Siddiqui, Faheema, Khalid, Muhammad Usaid, Farooqui, Waqas Ahmed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452628/
https://www.ncbi.nlm.nih.gov/pubmed/37626711
http://dx.doi.org/10.3390/biomedicines11082214

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