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BHLHE40 Maintains the Stemness of PαS Cells In Vitro by Targeting Zbp1 through the Wnt/β-Catenin Signaling Pathway

Primary bone mesenchymal stem cells (BMSCs) gradually lose stemness during in vitro expansion, which significantly affects the cell therapeutic effects. Here, we chose murine PαS (SCA-1(+)PDGFRα(+)CD45(−)TER119(−)) cells as representative of BMSCs and aimed to explore the premium culture conditions...

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Detalles Bibliográficos
Autores principales: Hu, Menglong, Tian, Yueming, Liu, Xuenan, Guo, Qian, Lu, Dazhuang, Wang, Xu, Lv, Longwei, Zhang, Xiao, Liu, Yunsong, Zhou, Yongsheng, Zhang, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452820/
https://www.ncbi.nlm.nih.gov/pubmed/37626688
http://dx.doi.org/10.3390/biomedicines11082190