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The Poly-Arginine Peptide R18D Interferes with the Internalisation of α-Synuclein Pre-Formed Fibrils in STC-1 Enteroendocrine Cells

In Parkinson’s disease (PD), gut inflammation is hypothesised to contribute to α-synuclein aggregation, but gastrointestinal α-synuclein expression is poorly characterised. Cationic arginine-rich peptides (CARPs) are an emerging therapeutic option that exerts various neuroprotective effects and may...

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Detalles Bibliográficos
Autores principales: Gorecki, Anastazja M., Spencer, Holly, Meloni, Bruno P., Anderton, Ryan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10452853/
https://www.ncbi.nlm.nih.gov/pubmed/37626586
http://dx.doi.org/10.3390/biomedicines11082089