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Opposing Roles of Blood-Borne Monocytes and Tissue-Resident Macrophages in Limbal Stem Cell Damage after Ocular Injury

Limbal stem cell (LSC) deficiency is a frequent and severe complication after chemical injury to the eye. Previous studies have assumed this is mediated directly by the caustic agent. Here we show that LSC damage occurs through immune cell mediators, even without direct injury to LSCs. In particular...

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Detalles Bibliográficos
Autores principales: Zhou, Chengxin, Lei, Fengyang, Mittermaier, Mirja, Ksander, Bruce, Dana, Reza, Dohlman, Claes H., Vavvas, Demetrios G., Chodosh, James, Paschalis, Eleftherios I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453077/
https://www.ncbi.nlm.nih.gov/pubmed/37626899
http://dx.doi.org/10.3390/cells12162089