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Opposing Roles of Blood-Borne Monocytes and Tissue-Resident Macrophages in Limbal Stem Cell Damage after Ocular Injury
Limbal stem cell (LSC) deficiency is a frequent and severe complication after chemical injury to the eye. Previous studies have assumed this is mediated directly by the caustic agent. Here we show that LSC damage occurs through immune cell mediators, even without direct injury to LSCs. In particular...
Autores principales: | Zhou, Chengxin, Lei, Fengyang, Mittermaier, Mirja, Ksander, Bruce, Dana, Reza, Dohlman, Claes H., Vavvas, Demetrios G., Chodosh, James, Paschalis, Eleftherios I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453077/ https://www.ncbi.nlm.nih.gov/pubmed/37626899 http://dx.doi.org/10.3390/cells12162089 |
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