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Ex Vivo Chromosomal Radiosensitivity Testing in Patients with Pathological Germline Variants in Breast Cancer High-Susceptibility Genes BReast CAncer 1 and BReast CAncer 2
Background: Individual radiosensitivity is an important factor in the occurrence of undesirable consequences of radiotherapy. The potential for increased radiosensitivity has been linked to highly penetrant heterozygous mutations in DNA repair genes such as BRCA1 and BRCA2. By studying the chromosom...
Autores principales: | Zuhair Kassem, Tara, Wunderle, Marius, Kuhlmann, Lukas, Ruebner, Matthias, Huebner, Hanna, Hoyer, Juliane, Reis, André, Fasching, Peter A., Beckmann, Matthias W., Hack, Carolin C., Fietkau, Rainer, Distel, Luitpold |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453196/ https://www.ncbi.nlm.nih.gov/pubmed/37623237 http://dx.doi.org/10.3390/cimb45080418 |
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