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PFKFB3-Mediated Glycolysis Boosts Fibroblast Activation and Subsequent Kidney Fibrosis

Renal fibrosis, a hallmark of chronic kidney diseases, is driven by the activation of renal fibroblasts. Recent studies have highlighted the role of glycolysis in this process. Nevertheless, one critical glycolytic activator, 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (PFKFB3), remains u...

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Detalles Bibliográficos
Autores principales: Yang, Qiuhua, Huo, Emily, Cai, Yongfeng, Zhang, Zhidan, Dong, Charles, Asara, John M., Wei, Qingqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453197/
https://www.ncbi.nlm.nih.gov/pubmed/37626891
http://dx.doi.org/10.3390/cells12162081

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