The Activation of the LIMK/Cofilin Signaling Pathway via Extracellular Matrix–Integrin Interactions Is Critical for the Generation of Mature and Vascularized Cardiac Organoids

The generation of mature and vascularized human pluripotent stem cell-derived cardiac organoids (hPSC-COs) is necessary to ensure the validity of drug screening and disease modeling. This study investigates the effects of cellular aggregate (CA) stemness and self-organization on the generation of ma...

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Detalles Bibliográficos
Autores principales: Noh, Ji-Min, Choi, Seung-Cheol, Song, Myeong-Hwa, Kim, Kyung Seob, Jun, Seongmin, Park, Jae Hyoung, Kim, Ju Hyeon, Kim, Kyoungmi, Ko, Tae Hee, Choi, Jong-Il, Gim, Jeong-An, Kim, Jong-Hoon, Jang, Yongjun, Park, Yongdoo, Na, Ji Eun, Rhyu, Im Joo, Lim, Do-Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453200/
https://www.ncbi.nlm.nih.gov/pubmed/37626839
http://dx.doi.org/10.3390/cells12162029

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