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Reduction of Ca(2+) Entry by a Specific Block of KCa3.1 Channels Optimizes Cytotoxic Activity of NK Cells against T-ALL Jurkat Cells
Degranulation mediated killing mechanism by NK cells is dependent on store-operated Ca(2+) entry (SOCE) and has optimum at moderate intracellular Ca(2+) elevations so that partial block of SOCE optimizes the killing process. In this study, we tested the effect of the selective blocker of KCa3.1 chan...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453324/ https://www.ncbi.nlm.nih.gov/pubmed/37626875 http://dx.doi.org/10.3390/cells12162065 |