An Improved Protocol for Targeted Differentiation of Primed Human Induced Pluripotent Stem Cells into HLA-G-Expressing Trophoblasts to Enable the Modeling of Placenta-Related Disorders

Abnormalities at any stage of trophoblast development may result in pregnancy-related complications. Many of these adverse outcomes are discovered later in pregnancy, but the underlying pathomechanisms are constituted during the first trimester. Acquiring developmentally relevant material to elucida...

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Detalles Bibliográficos
Autores principales: Shum, Ian O., Merkert, Sylvia, Malysheva, Svitlana, Jahn, Kirsten, Lachmann, Nico, Verboom, Murielle, Frieling, Helge, Hallensleben, Michael, Martin, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453333/
https://www.ncbi.nlm.nih.gov/pubmed/37626882
http://dx.doi.org/10.3390/cells12162070

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