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Probiotics and Fecal Transplant: An Intervention in Delaying Chronic Kidney Disease Progression?
Chronic kidney disease (CKD) is a global health challenge affecting nearly 700 million people worldwide. In the United States alone, the Medicare costs for CKD management has reached nearly USD 80 billion per year. While reversing CKD may be possible in the future, current strategies aim to slow its...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453439/ https://www.ncbi.nlm.nih.gov/pubmed/37623261 http://dx.doi.org/10.3390/clinpract13040080 |
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author | Sanekommu, Harshavardhan Taj, Sobaan Mah Noor, Rida Umair Akmal, Muhammad Akhtar, Reza Hossain, Mohammad Asif, Arif |
author_facet | Sanekommu, Harshavardhan Taj, Sobaan Mah Noor, Rida Umair Akmal, Muhammad Akhtar, Reza Hossain, Mohammad Asif, Arif |
author_sort | Sanekommu, Harshavardhan |
collection | PubMed |
description | Chronic kidney disease (CKD) is a global health challenge affecting nearly 700 million people worldwide. In the United States alone, the Medicare costs for CKD management has reached nearly USD 80 billion per year. While reversing CKD may be possible in the future, current strategies aim to slow its progression. For the most part, current management strategies have focused on employing Renin Angiotensin Aldosterone (RAS) inhibitors and optimizing blood pressure and diabetes mellitus control. Emerging data are showing that a disruption of the gut–kidney axis has a significant impact on delaying CKD progression. Recent investigations have documented promising results in using microbiota-based interventions to better manage CKD. This review will summarize the current evidence and explore future possibilities on the use of probiotics, prebiotics, synbiotics, and fecal microbial transplant to reduce CKD progression. |
format | Online Article Text |
id | pubmed-10453439 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-104534392023-08-26 Probiotics and Fecal Transplant: An Intervention in Delaying Chronic Kidney Disease Progression? Sanekommu, Harshavardhan Taj, Sobaan Mah Noor, Rida Umair Akmal, Muhammad Akhtar, Reza Hossain, Mohammad Asif, Arif Clin Pract Opinion Chronic kidney disease (CKD) is a global health challenge affecting nearly 700 million people worldwide. In the United States alone, the Medicare costs for CKD management has reached nearly USD 80 billion per year. While reversing CKD may be possible in the future, current strategies aim to slow its progression. For the most part, current management strategies have focused on employing Renin Angiotensin Aldosterone (RAS) inhibitors and optimizing blood pressure and diabetes mellitus control. Emerging data are showing that a disruption of the gut–kidney axis has a significant impact on delaying CKD progression. Recent investigations have documented promising results in using microbiota-based interventions to better manage CKD. This review will summarize the current evidence and explore future possibilities on the use of probiotics, prebiotics, synbiotics, and fecal microbial transplant to reduce CKD progression. MDPI 2023-08-01 /pmc/articles/PMC10453439/ /pubmed/37623261 http://dx.doi.org/10.3390/clinpract13040080 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Opinion Sanekommu, Harshavardhan Taj, Sobaan Mah Noor, Rida Umair Akmal, Muhammad Akhtar, Reza Hossain, Mohammad Asif, Arif Probiotics and Fecal Transplant: An Intervention in Delaying Chronic Kidney Disease Progression? |
title | Probiotics and Fecal Transplant: An Intervention in Delaying Chronic Kidney Disease Progression? |
title_full | Probiotics and Fecal Transplant: An Intervention in Delaying Chronic Kidney Disease Progression? |
title_fullStr | Probiotics and Fecal Transplant: An Intervention in Delaying Chronic Kidney Disease Progression? |
title_full_unstemmed | Probiotics and Fecal Transplant: An Intervention in Delaying Chronic Kidney Disease Progression? |
title_short | Probiotics and Fecal Transplant: An Intervention in Delaying Chronic Kidney Disease Progression? |
title_sort | probiotics and fecal transplant: an intervention in delaying chronic kidney disease progression? |
topic | Opinion |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453439/ https://www.ncbi.nlm.nih.gov/pubmed/37623261 http://dx.doi.org/10.3390/clinpract13040080 |
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