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Spatio-Temporal Patterns of the SARS-CoV-2 Epidemic in Germany

Results from an explorative study revealing spatio-temporal patterns of the SARS-CoV-2/ COVID-19 epidemic in Germany are presented. We dispense with contestable model assumptions and show the intrinsic spatio-temporal patterns of the epidemic dynamics. The analysis is based on COVID-19 incidence dat...

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Autor principal: Diebner, Hans H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453630/
https://www.ncbi.nlm.nih.gov/pubmed/37628167
http://dx.doi.org/10.3390/e25081137
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author Diebner, Hans H.
author_facet Diebner, Hans H.
author_sort Diebner, Hans H.
collection PubMed
description Results from an explorative study revealing spatio-temporal patterns of the SARS-CoV-2/ COVID-19 epidemic in Germany are presented. We dispense with contestable model assumptions and show the intrinsic spatio-temporal patterns of the epidemic dynamics. The analysis is based on COVID-19 incidence data, which are age-stratified and spatially resolved at the county level, provided by the Federal Government’s Public Health Institute of Germany (RKI) for public use. Although the 400 county-related incidence time series shows enormous heterogeneity, both with respect to temporal features as well as spatial distributions, the counties’ incidence curves organise into well-distinguished clusters that coincide with East and West Germany. The analysis is based on dimensionality reduction, multidimensional scaling, network analysis, and diversity measures. Dynamical changes are captured by means of difference-in-difference methods, which are related to fold changes of the effective reproduction numbers. The age-related dynamical patterns suggest a considerably stronger impact of children, adolescents and seniors on the epidemic activity than previously expected. Besides these concrete interpretations, the work mainly aims at providing an atlas for spatio-temporal patterns of the epidemic, which serves as a basis to be further explored with the expertise of different disciplines, particularly sociology and policy makers. The study should also be understood as a methodological contribution to getting a handle on the unusual complexity of the COVID-19 pandemic.
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spelling pubmed-104536302023-08-26 Spatio-Temporal Patterns of the SARS-CoV-2 Epidemic in Germany Diebner, Hans H. Entropy (Basel) Article Results from an explorative study revealing spatio-temporal patterns of the SARS-CoV-2/ COVID-19 epidemic in Germany are presented. We dispense with contestable model assumptions and show the intrinsic spatio-temporal patterns of the epidemic dynamics. The analysis is based on COVID-19 incidence data, which are age-stratified and spatially resolved at the county level, provided by the Federal Government’s Public Health Institute of Germany (RKI) for public use. Although the 400 county-related incidence time series shows enormous heterogeneity, both with respect to temporal features as well as spatial distributions, the counties’ incidence curves organise into well-distinguished clusters that coincide with East and West Germany. The analysis is based on dimensionality reduction, multidimensional scaling, network analysis, and diversity measures. Dynamical changes are captured by means of difference-in-difference methods, which are related to fold changes of the effective reproduction numbers. The age-related dynamical patterns suggest a considerably stronger impact of children, adolescents and seniors on the epidemic activity than previously expected. Besides these concrete interpretations, the work mainly aims at providing an atlas for spatio-temporal patterns of the epidemic, which serves as a basis to be further explored with the expertise of different disciplines, particularly sociology and policy makers. The study should also be understood as a methodological contribution to getting a handle on the unusual complexity of the COVID-19 pandemic. MDPI 2023-07-29 /pmc/articles/PMC10453630/ /pubmed/37628167 http://dx.doi.org/10.3390/e25081137 Text en © 2023 by the author. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Diebner, Hans H.
Spatio-Temporal Patterns of the SARS-CoV-2 Epidemic in Germany
title Spatio-Temporal Patterns of the SARS-CoV-2 Epidemic in Germany
title_full Spatio-Temporal Patterns of the SARS-CoV-2 Epidemic in Germany
title_fullStr Spatio-Temporal Patterns of the SARS-CoV-2 Epidemic in Germany
title_full_unstemmed Spatio-Temporal Patterns of the SARS-CoV-2 Epidemic in Germany
title_short Spatio-Temporal Patterns of the SARS-CoV-2 Epidemic in Germany
title_sort spatio-temporal patterns of the sars-cov-2 epidemic in germany
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453630/
https://www.ncbi.nlm.nih.gov/pubmed/37628167
http://dx.doi.org/10.3390/e25081137
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