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Iatrogenic Esophageal Perforation in Premature Infants: A Multicenter Retrospective Study from Poland

Greater awareness of possible iatrogenic esophageal perforation (EP) is needed. Though rare, EP is a legitimate health risk as it may lead to long-term morbidities. This study presents and discusses iatrogenic EP in a subset of preterm infants. Using radiographic images, we study and describe the co...

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Autores principales: Mikołajczak, Aleksandra, Kufel, Katarzyna, Żytyńska-Daniluk, Joanna, Rutkowska, Magdalena, Bokiniec, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453736/
https://www.ncbi.nlm.nih.gov/pubmed/37628398
http://dx.doi.org/10.3390/children10081399
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author Mikołajczak, Aleksandra
Kufel, Katarzyna
Żytyńska-Daniluk, Joanna
Rutkowska, Magdalena
Bokiniec, Renata
author_facet Mikołajczak, Aleksandra
Kufel, Katarzyna
Żytyńska-Daniluk, Joanna
Rutkowska, Magdalena
Bokiniec, Renata
author_sort Mikołajczak, Aleksandra
collection PubMed
description Greater awareness of possible iatrogenic esophageal perforation (EP) is needed. Though rare, EP is a legitimate health risk as it may lead to long-term morbidities. This study presents and discusses iatrogenic EP in a subset of preterm infants. Using radiographic images, we study and describe the consequences of the orogastric/nasogastric tube position (in radiographic images). We analyze the possible influence of histological chorioamnionitis on the development of esophageal perforation. This retrospective study examines the hospital records of 1149 preterm infants, 2009–2016, with very low birth weight (VLBW) and iatrogenic EP, comparing mortalities and morbidities between the two groups of preterm infants who had birth weights (BWs) of less than 750 g and were less than 27 weeks gestation age at birth: one group with iatrogenic esophageal perforation (EP group) and one group without perforation (non-EP group—the control group). Histopathological chorioamnionitis of the placenta showed no statistically significant differences between the groups. The only statistically significant difference was in the air leaks (p = 0.01). Three types of nasogastric tube (NGT) X-ray location were identified, depending on the place of the perforation: (1) high position below the carina mimicking esophageal atresia; (2) low, intra-abdominal; (3) NGT right pleura-directed. We also highlight the particular symptoms that may be indicative of EP due to a displacement of the nasogastric tube.
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spelling pubmed-104537362023-08-26 Iatrogenic Esophageal Perforation in Premature Infants: A Multicenter Retrospective Study from Poland Mikołajczak, Aleksandra Kufel, Katarzyna Żytyńska-Daniluk, Joanna Rutkowska, Magdalena Bokiniec, Renata Children (Basel) Article Greater awareness of possible iatrogenic esophageal perforation (EP) is needed. Though rare, EP is a legitimate health risk as it may lead to long-term morbidities. This study presents and discusses iatrogenic EP in a subset of preterm infants. Using radiographic images, we study and describe the consequences of the orogastric/nasogastric tube position (in radiographic images). We analyze the possible influence of histological chorioamnionitis on the development of esophageal perforation. This retrospective study examines the hospital records of 1149 preterm infants, 2009–2016, with very low birth weight (VLBW) and iatrogenic EP, comparing mortalities and morbidities between the two groups of preterm infants who had birth weights (BWs) of less than 750 g and were less than 27 weeks gestation age at birth: one group with iatrogenic esophageal perforation (EP group) and one group without perforation (non-EP group—the control group). Histopathological chorioamnionitis of the placenta showed no statistically significant differences between the groups. The only statistically significant difference was in the air leaks (p = 0.01). Three types of nasogastric tube (NGT) X-ray location were identified, depending on the place of the perforation: (1) high position below the carina mimicking esophageal atresia; (2) low, intra-abdominal; (3) NGT right pleura-directed. We also highlight the particular symptoms that may be indicative of EP due to a displacement of the nasogastric tube. MDPI 2023-08-16 /pmc/articles/PMC10453736/ /pubmed/37628398 http://dx.doi.org/10.3390/children10081399 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Mikołajczak, Aleksandra
Kufel, Katarzyna
Żytyńska-Daniluk, Joanna
Rutkowska, Magdalena
Bokiniec, Renata
Iatrogenic Esophageal Perforation in Premature Infants: A Multicenter Retrospective Study from Poland
title Iatrogenic Esophageal Perforation in Premature Infants: A Multicenter Retrospective Study from Poland
title_full Iatrogenic Esophageal Perforation in Premature Infants: A Multicenter Retrospective Study from Poland
title_fullStr Iatrogenic Esophageal Perforation in Premature Infants: A Multicenter Retrospective Study from Poland
title_full_unstemmed Iatrogenic Esophageal Perforation in Premature Infants: A Multicenter Retrospective Study from Poland
title_short Iatrogenic Esophageal Perforation in Premature Infants: A Multicenter Retrospective Study from Poland
title_sort iatrogenic esophageal perforation in premature infants: a multicenter retrospective study from poland
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453736/
https://www.ncbi.nlm.nih.gov/pubmed/37628398
http://dx.doi.org/10.3390/children10081399
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