Cargando…

KLVFF Conjugated Curcumin Microemulsion-Based Hydrogel for Transnasal Route: Formulation Development, Optimization, Physicochemical Characterization, and Ex Vivo Evaluation

Curcumin is a potent natural compound used to treat Alzheimer’s disease (AD). However, the clinical usefulness of curcumin to treat AD is restricted by its low oral bioavailability and difficulty permeating the blood-brain barrier. To overcome such drawbacks, various alternative strategies have been...

Descripción completa

Detalles Bibliográficos
Autores principales:	Phongpradist, Rungsinee, Jiaranaikulwanitch, Jutamas, Thongkorn, Kriangkrai, Lekawanvijit, Suree, Sirilun, Sasithorn, Chittasupho, Chuda, Poomanee, Worrapan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453774/ https://www.ncbi.nlm.nih.gov/pubmed/37623065 http://dx.doi.org/10.3390/gels9080610

Ejemplares similares

Surface Modification of Curcumin Microemulsions by Coupling of KLVFF Peptide: A Prototype for Targeted Bifunctional Microemulsions
por: Phongpradist, Rungsinee, et al.
Publicado: (2022)

Validated HPTLC and antioxidant activities for quality control of catechin in a fermented tea (Camellia sinensis var. assamica)
por: Thammarat, Phanit, et al.
Publicado: (2021)

Targeting Spike Glycoprotein S1 Mediated by NLRP3 Inflammasome Machinery and the Cytokine Releases in A549 Lung Epithelial Cells by Nanocurcumin
por: Chittasupho, Chuda, et al.
Publicado: (2023)

Stability and solubility improvement of Sompoi (Acacia concinna Linn.) pod extract by topical microemulsion
por: Poomanee, Worrapan, et al.
Publicado: (2017)

The in vitro effects of black soldier fly larvae (Hermitia illucens) oil as a high-functional active ingredient for inhibiting hyaluronidase, anti-oxidation benefits, whitening, and UVB protection
por: Phongpradist, Rungsinee, et al.
Publicado: (2023)

Phytochemical, Antioxidant, Antihyaluronidase, Antityrosinase, and Antimicrobial Properties of Nicotiana tabacum L. Leaf Extracts
por: Prommaban, Adchara, et al.
Publicado: (2022)

Ultraviolet Radiation Protective and Anti-Inflammatory Effects of Kaempferia galanga L. Rhizome Oil and Microemulsion: Formulation, Characterization, and Hydrogel Preparation
por: Chittasupho, Chuda, et al.
Publicado: (2022)

Emulgels Containing Perilla frutescens Seed Oil, Moringa oleifera Seed Oil, and Mixed Seed Oil: Microemulsion and Safety Assessment
por: Tunit, Prakairat, et al.
Publicado: (2022)

Cardiotoxicity of Uremic Toxins: A Driver of Cardiorenal Syndrome
por: Lekawanvijit, Suree
Publicado: (2018)

Optimization of Mangifera indica L. Kernel Extract-Loaded Nanoemulsions via Response Surface Methodology, Characterization, Stability, and Skin Permeation for Anti-Acne Cosmeceutical Application
por: Poomanee, Worrapan, et al.
Publicado: (2020)

Optimized multiherbal combination and in vivo anti-skin aging potential: a randomized double blind placebo controlled study
por: Poomanee, Worrapan, et al.
Publicado: (2023)

Utilization of Emulsion Inversion to Fabricate Tea (Camellia sinensis L.) Flower Extract Obtained by Supercritical Fluid Extraction-Loaded Nanoemulsions
por: Yaowiwat, Nara, et al.
Publicado: (2023)

Preclinical Study of Ibuprofen Loaded Transnasal Mucoadhesive Microemulsion for Neuroprotective Effect in MPTP Mice Model
por: Mandal, Surjyanarayan, et al.
Publicado: (2018)

Effects of Quercetin and Curcumin Combination on Antibacterial, Antioxidant, In Vitro Wound Healing and Migration of Human Dermal Fibroblast Cells
por: Chittasupho, Chuda, et al.
Publicado: (2021)

Synergistic Antioxidant Activity and Enhanced Stability of Curcumin Encapsulated in Vegetal Oil-Based Microemulsion and Gel Microemulsions
por: Scomoroscenco, Cristina, et al.
Publicado: (2022)

Physicochemical and prebiotic properties of resistant starch from Musa sapientum Linn., ABB group, cv. Kluai Namwa Luang
por: Jaiturong, Patthanakorn, et al.
Publicado: (2020)

Histological assessment of the human heart valves and its relationship with age
por: Gumpangseth, Treerat, et al.
Publicado: (2020)

Esophageal squamous cell carcinoma metastasizing to the oral cavity: a case report and literature review
por: Sittitrai, Pichit, et al.
Publicado: (2023)

Formulation and kinetic modeling of curcumin loaded intranasal mucoadhesive microemulsion
por: Patel, Mikesh B., et al.
Publicado: (2012)

The Anti-Aggregative Peptide KLVFF Mimics Aβ1-40 in the Modulation of Nicotinic Receptors: Implications for Peptide-Based Therapy
por: Trebesova, Hanna, et al.
Publicado: (2022)

From BACE1 Inhibitor to Multifunctionality of Tryptoline and Tryptamine Triazole Derivatives for Alzheimer’s Disease
por: Jiaranaikulwanitch, Jutamas, et al.
Publicado: (2012)

Novel Gel Microemulsion as Topical Drug Delivery System for Curcumin in Dermatocosmetics
por: Scomoroscenco, Cristina, et al.
Publicado: (2021)

Docosahexaenoic acid–mediated, targeted and sustained brain delivery of curcumin microemulsion
por: Shinde, Rajshree L., et al.
Publicado: (2017)

Rosmarinic Acid Enriched Fraction from Perilla frutescens Leaves Strongly Protects Indomethacin-Induced Gastric Ulcer in Rats
por: Kangwan, Napapan, et al.
Publicado: (2019)

Profiling the Expression and Prognostic Values of FYN, A Non-Receptor Tyrosine Kinase, in Different Histological Types of Epithelial Ovarian Cancer
por: Dankai, Wiyada, et al.
Publicado: (2023)

FLT3, a prognostic biomarker for acute myeloid leukemia (AML): Quantitative monitoring with a simple anti‐FLT3 interaction and flow cytometric method
por: Ampasavate, Chadarat, et al.
Publicado: (2019)

Dataset of (1)H-nuclear magnetic resonance and mass spectra of surface modified Poly(amidoamine) dendrimers with LFC131 peptide
por: Chittasupho, Chuda, et al.
Publicado: (2021)

Influence of Benincasa hispida Peel Extracts on Antioxidant and Anti-Aging Activities, including Molecular Docking Simulation
por: Phumat, Pimpak, et al.
Publicado: (2023)

Ethanolic Extract Propolis-Loaded Niosomes Diminish Phospholipase B1, Biofilm Formation, and Intracellular Replication of Cryptococcus neoformans in Macrophages
por: Kietrungruang, Kritapat, et al.
Publicado: (2023)

Preparation and In Vitro Characterization of Alkyl Polyglucoside-Based Microemulsion for Topical Administration of Curcumin
por: Scomoroscenco, Cristina, et al.
Publicado: (2023)

High Prevalence of Human Papillomavirus Type 18 in Oral Potentially Malignant Disorders in Thailand
por: Kaewmaneenuan, Nithi, et al.
Publicado: (2021)

Curcumin: Overview of Extraction Methods, Health Benefits, and Encapsulation and Delivery Using Microemulsions and Nanoemulsions
por: Ciuca, Maria D., et al.
Publicado: (2023)

Microemulsion-Based Keratin–Chitosan Gel for Improvement of Skin Permeation/Retention and Activity of Curcumin
por: Niu, Jiangxiu, et al.
Publicado: (2023)

Potential Anti-Alzheimer Agents from Guanidinyl Tryptophan Derivatives with Activities of Membrane Adhesion and Conformational Transition Inhibitions
por: Wongrattanakamon, Pathomwat, et al.
Publicado: (2021)

Bone regeneration of a polymeric sponge technique—Alloplastic bone substitute materials compared with a commercial synthetic bone material (MBCP+TM technology): A histomorphometric study in porcine skull
por: Intapibool, Punyada, et al.
Publicado: (2021)

Wound healing activity of Pluchea indica leaf extract in oral mucosal cell line and oral spray formulation containing nanoparticles of the extract
por: Buranasukhon, Wiphupat, et al.
Publicado: (2017)

Hydrogel Containing Borassus flabellifer L. Male Flower Extract for Antioxidant, Antimicrobial, and Anti-Inflammatory Activity
por: Tunit, Prakairat, et al.
Publicado: (2022)

Cell-free supernatants from cultures of lactic acid bacteria isolated from fermented grape as biocontrol against Salmonella Typhi and Salmonella Typhimurium virulence via autoinducer-2 and biofilm interference
por: Pelyuntha, Wattana, et al.
Publicado: (2019)

Organic acids and 2,4-Di-tert-butylphenol: major compounds of Weissella confusa WM36 cell-free supernatant against growth, survival and virulence of Salmonella Typhi
por: Pelyuntha, Wattana, et al.
Publicado: (2020)

Endoscopic Transnasal Odontoidectomy
por: Zoia, Cesare, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ajl6ja0m782953ljk5r779e3bg