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Infantile Haemangioma in the Romanian Paediatric Population—Characteristics and Therapeutic Approaches

Infantile haemangioma (IH) is the most common benign tumour in childhood, with an incidence of 4% to 12%. Aim: to describe the characteristics of infantile haemangioma in a sample of Romanian children <2 years old at diagnosis, types of treatment applied, recorded complications and the response t...

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Autores principales: Raicu, Anca-Maria, Danila, George-Florin, Secheli, Ionut Fernando, Bratu, Eugenia Claudia, Minca, Dana Galieta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453925/
https://www.ncbi.nlm.nih.gov/pubmed/37628313
http://dx.doi.org/10.3390/children10081314
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author Raicu, Anca-Maria
Danila, George-Florin
Secheli, Ionut Fernando
Bratu, Eugenia Claudia
Minca, Dana Galieta
author_facet Raicu, Anca-Maria
Danila, George-Florin
Secheli, Ionut Fernando
Bratu, Eugenia Claudia
Minca, Dana Galieta
author_sort Raicu, Anca-Maria
collection PubMed
description Infantile haemangioma (IH) is the most common benign tumour in childhood, with an incidence of 4% to 12%. Aim: to describe the characteristics of infantile haemangioma in a sample of Romanian children <2 years old at diagnosis, types of treatment applied, recorded complications and the response to the therapeutic approach. A two-year prospective case series study (August 2019 to August 2021) was carried out. Sample: 117 patients <24 months of age diagnosed with IH at the Emergency Hospital for Children “Marie Sklodowska Curie”, in Bucharest, Romania. Five therapeutic approaches were used: oral treatment with propranolol, local treatment with timolol, surgical treatment, topical treatment with steroids and no treatment (“wait and see”). Recorded factors mentioned in the literature were also present in this study population: female patients—68.4%; phototype I—58%. In 53% of cases, IHs had a head and neck location and 10% developed local complications (traumatic bleeding). The majority of patients (86%) required one type of therapy: oral propranolol (51%). A low relapse rate was recorded (4%). We consider that any child with a vascular anomaly should be referred to a highly specialised medical service for therapeutic approach.
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spelling pubmed-104539252023-08-26 Infantile Haemangioma in the Romanian Paediatric Population—Characteristics and Therapeutic Approaches Raicu, Anca-Maria Danila, George-Florin Secheli, Ionut Fernando Bratu, Eugenia Claudia Minca, Dana Galieta Children (Basel) Article Infantile haemangioma (IH) is the most common benign tumour in childhood, with an incidence of 4% to 12%. Aim: to describe the characteristics of infantile haemangioma in a sample of Romanian children <2 years old at diagnosis, types of treatment applied, recorded complications and the response to the therapeutic approach. A two-year prospective case series study (August 2019 to August 2021) was carried out. Sample: 117 patients <24 months of age diagnosed with IH at the Emergency Hospital for Children “Marie Sklodowska Curie”, in Bucharest, Romania. Five therapeutic approaches were used: oral treatment with propranolol, local treatment with timolol, surgical treatment, topical treatment with steroids and no treatment (“wait and see”). Recorded factors mentioned in the literature were also present in this study population: female patients—68.4%; phototype I—58%. In 53% of cases, IHs had a head and neck location and 10% developed local complications (traumatic bleeding). The majority of patients (86%) required one type of therapy: oral propranolol (51%). A low relapse rate was recorded (4%). We consider that any child with a vascular anomaly should be referred to a highly specialised medical service for therapeutic approach. MDPI 2023-07-30 /pmc/articles/PMC10453925/ /pubmed/37628313 http://dx.doi.org/10.3390/children10081314 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Raicu, Anca-Maria
Danila, George-Florin
Secheli, Ionut Fernando
Bratu, Eugenia Claudia
Minca, Dana Galieta
Infantile Haemangioma in the Romanian Paediatric Population—Characteristics and Therapeutic Approaches
title Infantile Haemangioma in the Romanian Paediatric Population—Characteristics and Therapeutic Approaches
title_full Infantile Haemangioma in the Romanian Paediatric Population—Characteristics and Therapeutic Approaches
title_fullStr Infantile Haemangioma in the Romanian Paediatric Population—Characteristics and Therapeutic Approaches
title_full_unstemmed Infantile Haemangioma in the Romanian Paediatric Population—Characteristics and Therapeutic Approaches
title_short Infantile Haemangioma in the Romanian Paediatric Population—Characteristics and Therapeutic Approaches
title_sort infantile haemangioma in the romanian paediatric population—characteristics and therapeutic approaches
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10453925/
https://www.ncbi.nlm.nih.gov/pubmed/37628313
http://dx.doi.org/10.3390/children10081314
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