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Spatial Transcriptomic Analysis of Focal and Normal Areas of Myocyte Disarray in Human Hypertrophic Cardiomyopathy

Hypertrophic Cardiomyopathy (HCM) is a common inherited disorder that can lead to heart failure and sudden cardiac death, characterized at the histological level by focal areas of myocyte disarray, hypertrophy and fibrosis, and only a few disease-targeted therapies exist. To identify the focal and s...

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Detalles Bibliográficos
Autores principales: Laird, Jason, Perera, Gayani, Batorsky, Rebecca, Wang, Hongjie, Arkun, Knarik, Chin, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454036/
https://www.ncbi.nlm.nih.gov/pubmed/37628806
http://dx.doi.org/10.3390/ijms241612625