Cargando…
Cytoprotective, Cytotoxic and Cytostatic Roles of Autophagy in Response to BET Inhibitors
The bromodomain and extra-terminal domain (BET) family inhibitors are small molecules that target the dysregulated epigenetic readers, BRD2, BRD3, BRD4 and BRDT, at various transcription-related sites, including super-enhancers. BET inhibitors are currently under investigation both in pre-clinical c...
Autores principales: | Elshazly, Ahmed M., Gewirtz, David A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454099/ https://www.ncbi.nlm.nih.gov/pubmed/37628849 http://dx.doi.org/10.3390/ijms241612669 |
Ejemplares similares
-
The Cytoprotective Role of Autophagy in Response to BRAF-Targeted Therapies
por: Elshazly, Ahmed M., et al.
Publicado: (2023) -
The Cytoprotective, Cytotoxic and Nonprotective Functional Forms of Autophagy Induced by Microtubule Poisons in Tumor Cells—Implications for Autophagy Modulation as a Therapeutic Strategy
por: Xu, Jingwen, et al.
Publicado: (2022) -
Is autophagy induction by PARP inhibitors a target for therapeutic benefit?
por: ELSHAZLY, AHMED M., et al.
Publicado: (2022) -
Is Autophagy Inhibition in Combination with Temozolomide a Therapeutically Viable Strategy?
por: Elshazly, Ahmed M., et al.
Publicado: (2023) -
Making the Case for Autophagy Inhibition as a Therapeutic Strategy in Combination with Androgen-Targeted Therapies in Prostate Cancer
por: Elshazly, Ahmed M., et al.
Publicado: (2023)