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Endocytosis and Endocytic Motifs across the Connexin Gene Family

Proteins fated to be internalized by clathrin-mediated endocytosis require an endocytic motif, where AP-2 or another adaptor protein can bind and recruit clathrin. Tyrosine and di-leucine-based sorting signals are such canonical motifs. Connexin 43 (Cx43) has three canonical tyrosine-based endocytic...

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Detalles Bibliográficos
Autores principales: Fisher, Charles G., Falk, Matthias M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454166/
https://www.ncbi.nlm.nih.gov/pubmed/37629031
http://dx.doi.org/10.3390/ijms241612851