Scopoletin Reactivates Latent HIV-1 by Inducing NF-κB Expression without Global T Cell Activation

Reversing HIV-1 latency promotes the killing of infected cells and is essential for cure strategies. However, current latency-reversing agents (LRAs) are not entirely effective and safe in activating latent viruses in patients. In this study, we investigated whether Scopoletin (6-Methoxy-7-hydroxyco...

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Detalles Bibliográficos
Autores principales: Zhu, Yuqi, Jiang, Zhengtao, Liu, Lin, Yang, Xinyi, Li, Min, Cheng, Yipeng, Xu, Jianqing, Yin, Chunhua, Zhu, Huanzhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454185/
https://www.ncbi.nlm.nih.gov/pubmed/37628826
http://dx.doi.org/10.3390/ijms241612649

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454185/
https://www.ncbi.nlm.nih.gov/pubmed/37628826
http://dx.doi.org/10.3390/ijms241612649

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