SARS-CoV-2 Spike Proteins and Cell–Cell Communication Induce P-Selectin and Markers of Endothelial Injury, NETosis, and Inflammation in Human Lung Microvascular Endothelial Cells and Neutrophils: Implications for the Pathogenesis of COVID-19 Coagulopathy

COVID-19 progression often involves severe lung injury, inflammation, coagulopathy, and leukocyte infiltration into pulmonary tissues. The pathogenesis of these complications is unknown. Because vascular endothelium and neutrophils express angiotensin-converting enzyme-2 and spike (S)-proteins, whic...

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Detalles Bibliográficos
Autores principales: Bhargavan, Biju, Kanmogne, Georgette D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454213/
https://www.ncbi.nlm.nih.gov/pubmed/37628764
http://dx.doi.org/10.3390/ijms241612585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454213/
https://www.ncbi.nlm.nih.gov/pubmed/37628764
http://dx.doi.org/10.3390/ijms241612585

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