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Melatonin Attenuates Oxidative Stress-Induced Apoptosis of Bovine Ovarian Granulosa Cells by Promoting Mitophagy via SIRT1/FoxO1 Signaling Pathway

Oxidative-stress-induced apoptosis of granulosa cells is considered to be a main driver of follicular atresia. Increasing evidence suggests a protective effect of melatonin against oxidative damage but the mechanism remains unclear. The aim of this study is to investigate the effects of melatonin on...

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Detalles Bibliográficos
Autores principales: Xu, Gaoqing, Dong, Yangyunyi, Wang, Zhe, Ding, He, Wang, Jun, Zhao, Jing, Liu, Hongyu, Lv, Wenfa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454225/
https://www.ncbi.nlm.nih.gov/pubmed/37629033
http://dx.doi.org/10.3390/ijms241612854