Acetaminophen impairs ferroptosis in the hippocampus of septic mice by regulating glutathione peroxidase 4 and ferroptosis suppressor protein 1 pathways

BACKGROUND: Neuronal ferroptosis is a major cause of cognitive impairment and mortality in patients with sepsis‐associated encephalopathy (SAE). A low dose of acetaminophen (APAP) in septic mice can prevent ferroptosis in the hippocampal tissue; however, the underlying mechanism is unknown. This stu...

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Detalles Bibliográficos
Autores principales: Chu, Jing, Li, Hong, Yuan, Zhihao, Zhou, Wenyu, Yu, Yang, Yu, Yonghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454284/
https://www.ncbi.nlm.nih.gov/pubmed/37443407
http://dx.doi.org/10.1002/brb3.3145

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454284/
https://www.ncbi.nlm.nih.gov/pubmed/37443407
http://dx.doi.org/10.1002/brb3.3145

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