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Clinical, Pathological and Molecular Insights on KRAS, NRAS, BRAF, PIK3CA and TP53 Mutations in Metastatic Colorectal Cancer Patients from Northeastern Romania

Mutations in RAS, BRAF, PIK3CA, and TP53 are well-established genetic abnormalities in metastatic colorectal cancer (mCRC). However, limited information is available for patients from Eastern Europe, including Romania. In this retrospective analysis, we investigated 104 mCRC patients from the Northe...

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Detalles Bibliográficos
Autores principales: Afrăsânie, Vlad-Adrian, Marinca, Mihai-Vasile, Gafton, Bogdan, Alexa-Stratulat, Teodora, Rusu, Alexandra, Froicu, Eliza-Maria, Sur, Daniel, Lungulescu, Cristian Virgil, Popovici, Larisa, Lefter, Andrei-Vlad, Afrăsânie, Irina, Ivanov, Anca-Viorica, Miron, Lucian, Rusu, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10454287/
https://www.ncbi.nlm.nih.gov/pubmed/37628868
http://dx.doi.org/10.3390/ijms241612679

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